主持科研项目：

 

　　1.国家自然科学基金面上项目（2013.01-2016.12，项目负责人）：

 

　　环境中N-亚硝基化合物分子结构与致癌活性关系及其生物标志物研究。

 

　　2.北京工业大学“京华人才”支持计划（2015.01-2017.12，项目负责人）：

 

　　新型靶向性亚硝基脲类抗癌药物的研究。

 

　　3.北京市留学人员科技活动择优资助项目（2015.01-2015.12，项目负责人）：

 

　　烟草特异亚硝胺导致肺癌的生物标志物研究。

 

　　4.国家自然科学基金青年基金项目（2010.01-2012.12，项目负责人）：

 

　　N-亚硝基化合物对DNA的损伤作用机制及相关构效关系。

 

　　5.北京市科技新星计划B类（2010.01-2012.12，项目负责人）：

 

　　N-亚硝基化合物对DNA的损伤作用及致癌机理研究。

 

　　6.北京市自然科学基金预探索项目（2011.01-2012.06，项目负责人）：

 

　　烷基亚硝胺对DNA的损伤作用与其致癌靶器官之间的关系。

 

　　7.北京市委组织部优秀人才资助项目（2008.01-2009.12，项目负责人）：

 

　　癌症相关标志物及应用研究。

　　主要学术论文：

 

　　1.Lili Li, Sisi Li, Guohui Sun, Ruizeng Peng, Lijiao Zhao,*Rugang Zhong. Influence of the expression Level of O-6-Alkylguanine-DNAAlkyltransferase on the Formation of DNA Interstrand Crosslinks Induced byChloroethylnitrosoureas in Cells: A Quantitation Using High-Performance LiquidChromatography-Mass Spectrometry. PlosOne, 2015, 10(3):UNSP e0121225 (SCI收录)

 

　　2.Guohui Sun, Lijiao Zhao,* Tengjiao Fan,Sisi Li, Rugang Zhong. Investigations on the effect of O6-benzylguanineon the formation of dG-dC interstrand crosslinks induced bychloroethylnitrosoureas in human glioma cells using a stable isotope dilutionhigh-performance liquid chromatography-electrospray ionization tandem massspectrometry. Chem. Res. Toxicol.,2014, 27(7): 1253-1262. (SCI收录)

 

　　3.Lili Li, Lijiao Zhao,* Rugang Zhong.Quanti？cation of DNAinterstrand crosslinks induced by ACNU in NIH/3T3 and L1210 cells usinghigh-performance liquid chromatography/ electrospray ionization tandemmassspectrometry. Rapid Comm. Mass Spectrom.,2014, 28(5): 439-447. (SCI收录)

 

　　4.Lijiao Zhao,* Lili Li, Jie Xu, Rugang Zhong. Comparative investigation of the DNA inter-strandcrosslinks induced by ACNU, BCNU, CCNU and FTMS using high-performance liquidchromatography-electrospray ionization tandem mass spectrometry. Int. J. Mass Spectrom., 2014,368(7):30-36. (SCI收录)

 

　　5.Lijiao Zhao, Silvia Balbo, Mingyao Wang, Pramod Upadhyaya, Samir S. Khariwala, Peter W. Villalta,Stephen S. Hecht*. Quantitation of pyridyloxobutyl- DNA adducts in tissues ofrats treated chronically with (R)- or(S)-N′-nitrosonornicotine (NNN) in acarcinogenicity study. Chem. Res.Toxicol., 2013, 26(10): 1526-1535. (SCI收录)

 

　　6.Tingting Liu, Lijiao Zhao,* Rugang Zhong.DFT study of phosphotriesters hydrolysis in aqueous solution: a model study forDNA single strand scission induced by N-nitrosoureas. J. Mol. Model., 2013, 19(2): 647-659. (SCI收录)

 

　　7.Lijiao Zhao,* Xinyan Ma, Rugang Zhong. A DFT investigation on theformation mechanisms of DNA interstrand crosslinks induced bychloroethylnitrosoureas. Int. J. QuantumChem., 2013, 113(9): 1299-1306. (SCI收录)

 

　　8.Ting Ren, Lijiao Zhao,* Bosi Sun, Rugang Zhong. Determination of lead, cadmium,copper, and nickel in the Tonghui River of Beijing, China, by cloud pointextraction-high resolution continuum source graphite furnace atomic absorptionspectrometry. J. Environ. Qual.,2013, 42(6): 1752-1762. (SCI收录)

 

　　9.Lijiao Zhao,* Xinyan Ma, Rugang Zhong. Comparative theoreticalinvestigation of the mechanism of DNA interstrand crosslinks induced by twoN-nitroso compounds: nitrosoureas andnitrosamines. J. Phy. Org. Chem.,2012, 25(12): 1153-1167. (SCI收录)

 

　　10.Jun Cao, Lijiao Zhao,* Shubin Jin, RugangZhong. Relationship between the molecular structure and the anticancer activityof N-(2-chloroethyl)-N'-c yclohexyl-N-nitrosoureas: A theoreticalinvestigation. Int. J. Quantum Chem.,2012, 112(3): 747-758. (SCI收录)

 

　　11.Lijiao Zhao,* Ting Ren, Rugang Zhong. Determination of lead in humanhair by high resolution continuum source graphite furnace atomic absorptionspectrometry with microwave digestion and solid sampling. Anal. Lett., 2012, 45(16): 2467-2481. (SCI收录)

 

　　12.Baoqing Bai, Lijiao Zhao,* Rugang Zhong.Quantification of meCCNU-induced dG-dC crosslinks in oligonucleotide duplexesby liquid chromatography/ electrospray ionization tandem mass spectrometry. Rapid Comm. Mass Spectrom., 2011,25(14): 2027-2034. (SCI收录)

 

　　13.Lijiao Zhao,* Tingting Liu, Rugang Zhong. A comparison of thestereoisomeric penta-coordinated phosphorus intermediates formed from 19dimethoxyl N-phosphoryl amino acids by DFT calculations. J. Theor. Comput. Chem., 2011, 10(2): 217-229.(SCI收录)