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陈永泉

浏览：143 来源：江南大学食品学院原文：

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承担教学
研究生培养

姓名：陈永泉	性别：男
民族：未填写	出生年份：1962
最高学历：研究生	学位：博士
1982年毕业于复旦大学微生物学系获学士学位，1990年毕业于比利时Free University of Brussels分子生物学系获博士学位，1993年在美国Wayne State University病理学系完成博士后研究后留校工作，2002-2012在美国Wake Forest University医学院工作。2012年回国，现为江南大学食品学院教授及功能脂质与健康卓越中心（Center of Excellence for Bioactive Lipid andHealth）主任。　　陈永泉教授研究方向为食品活性成分与人体健康及疾病预防, 研究兴趣主要集中在脂肪合成、代谢与癌症相互关系及机制。已在国际核心期刊上发表论文95余篇, 其中近50篇发表在SCI影响因子5.0以上杂志，是本领域国内外知名学者之一。作为会议主席或分会主席参加国际会议10次, 作大会报告和特邀报告66次。兼任25种英文杂志编委和审稿人, 是Frontiers in Bioscience, Nutrition and Dietary Supplements, CancerManagement and Research, Clinical Medicine: Urology, Integrative MedicineInsights编辑之一。是NIH (美国国立卫生健康研究院), DOD (美国国防部) 等90个美国及其他国家资助机构的评审专家组成员。曾获得NIH P01项目1项, NIHR01项目10项，从1993年来,共承担研究课题28项,研究课题总经费超过4000万美元, 其中作为PI的超过2000万美元。　　【受教育经历】　　1990/06-1993/02 美国Wayne State University病理学系博士后　　1984/06-1989/09 比利时Free University of Brussels分子生物学系博士学位　　1978/06-1982/08 复旦大学微生物与分子生物学学士学位　　【研究工作经历】　　2012/02 – 至今江南大学，食品学院教授，功能脂质与健康卓越中心主任　　2008/06 – 至今江南大学，长江学者讲座教授　　2005/06 – 至今美国Wake Forest University医学院，终身教授　　2002/01 – 至今美国Wake Forest University脂质研究中心，主任　　2002/01-2005/05 美国Wake Forest University医学院，副教授　　1998/06-2002/01 美国Wayne State University病理学系，副教授　　1993/03-1998/05 美国Wayne State University病理学系，助理教授

　　已发表的SCI收录论文（带*为责任作者）

　　1. Haiqin Chen, Zhennan Gu, Hao Zhang, Wei Chen, W.Todd Lowther, Yong Q. Chen*. expression and Purification of IntegralMembrane Fatty Acid Desaturases. PLoS One, In press, 2013.

　　2. Yong Q. Chen*, editor, Animal Models of Cancer,Cancer metastasis Reviews, 32 issue 1, 2013.

　　3. Janel Suburu and Yong Q. Chen*.Polyunsaturated Fatty Acids and Cancer Prevention. In Inflammation and Cancer:Mechanisms and Dietary Approaches for Cancer Prevention (A-N. T. Kong ed.) pp,2013, Taylor and Francis Group, Boca Raton, FL.

　　4. Janel Suburu and Yong Q. Chen*. Lipid andProstate Cancer. Prostaglandins & Other Lipid Mediators, 98: 1-10, 2012.

　　5. Tim Y. Hou, Jennifer M. Monk, Yang-Yi Fan, RolaBarhoumi, Yong Q. Chen, Gonzalo M. Rivera, David N. McMurray and RobertS. Chapkin. n-3 polyunsaturated fatty acids suppressphosphatidylinositol-(4,5)-bisphosphate 1 dependent actin remodeling duringCD4+ T cell activation. Biochemical Journal 443: 27-37, 2012.

　　6. Shihua Wang, Jiansheng Wu, Janel Suburu, ZhennanGu, Jiaozhong Cai, Linara S. Axanova, Scott D. Cramer, Michael J. Thomas, DonnaL. Perry, Iris Edwards, Lorelei Mucci, Jennifer Sinnott, Massimo Loda,Guangchao Sui, Isabelle M. Berquin and Yong Q. Chen*. Effect of DietaryPolyunsaturated Fatty Acids on Castration-resistant Prostate Cancer.Carcinogenesis 33: 404-412, 2012.

　　7. M. Katie Conley-LaComb, Wei Huang, Shihua Wang,Dongping Shi, Young Suk Jung, Abdo Najy, Rafael Fridman, R. Daniel Bonfil,Michael Cher, Yong Q. Chen and Hyeong-Reh Choi Kim. PTEN Regulates PDGFLigand Switch for β-PDGFR Signaling in Prostate Cancer. Am. J. Path. 180:1017-1027, 2012.

　　8. Isabelle M. Berquin, Iris J. Edwards, SteveKridel, Yong Q. Chen*. Polyunsaturated Fatty Acid metabolism in ProstateCancer. Cancer metast. Rev. 30: 295-309, 2011.

　　9. Axanova, L. S., Chen, Y. Q., McCoy, T.,Sui, G and Cramer, S. D. 1,25-dihydroxyvitamin D3 and PI3K/AKT inhibitorssynergistically inhibit growth and induce senescence in prostate cancer cells.Prostate 70:1658-1671, 2010.

　　10. Seaho Kim, Wei Huang, Emilio P. Mottillo, AnjumSohail, Yoon-Ah Ham, M. Katie Conley-LaComb, Chong Jai Kim, Guri Tzivion,Hyeong-Reh Choi Kim, Shihua Wang, Yong Q. Chen, and Rafael Fridman.Posttranslational regulation of membrane type-1 matrix metalloproteinase(MT1-MMP) in mouse Pten-null prostate cancer cells: enhance surface expressionand differential O-glycosylation of MT1-MMP1. BBA-Mol. Cell Res. 1803:1287–1297, 2010

　　11. Heidi J. Chial, Peter Lenart, and Yong Q.Chen*. APPL proteins FRET at the BAR: Direct observation of BARdomain-mediated interactions on cell membranes. PLoS One 5:e12471, 2010

　　12. Yunping Hu, Haiguo Sun, Rick T. Owens, ZhennanGu, Jiansheng Wu, Yong Q. Chen, Joseph T O’ Flaherty, Iris J. Edwards.Syndecan-1-dependent suppression of PDK1/Akt/Bad signaling by docosahexaenoicacid induces apoptosis in prostate cancer. Neoplasia 12: 826-836, 2010.

　　13. Haiguo Sun, Yunping Hu, Zhennan Gu, Martha D.Wilson, Yong Q. Chen, Lawrence L. Rudel, Mark C. Willingham and Iris J.Edwards. Endogenous synthesis of n-3 polyunsaturated fatty acids in Fat-1 miceis associated with increased mammary gland and liver syndecan-1. PLoS One6:e20502, 2011.

　　14. Haiguo Sun, Yunping Hu, Zhennan Gu, Rick T Owens,Yong Q Chen and Iris J Edwards. Omega-3 fatty acids induce apoptosis inhuman breast cancer cells and mouse mammary tissue through syndecan-1inhibition of the MEK-Erk pathway. Carcinogenesis 32: 1518-1524, 2011.

　　15. Hongchao Wang, Bo Yang, Yun Feng, Guangfei Hao,Haiqin Chen, Lu Feng, Yong Q. Chen, Hao Zhang, Lei Wang, Wei Chen.Biochemical characterization of Tetrahydrobiopterin synthesis pathway in fungusMortierella alpina. Microbiology 157: 3059-3070, 2011.

　　16. Lei Wang, Wei Chen, Yun Feng, Yan Ren, ZhennanGu, Haiqin Chen, Hongchao Wang, Michael J. Thomas, Baixi Zhang1, Isabelle M.Berquin5, Yang Li2, Jiansheng Wu5, Huanxin Zhang2, Yuanda Song1, Xiang Liu7,James S. Norris, Suriguga Wang, Peng Du, Junguo Shen, Na Wang, Yanlin Yang, WeiWang, Lu Feng, Colin Ratledge, Hao Zhang, and Yong Q. Chen*. GenomeCharacterization of the Oleaginous Fungus Mortierella alpina. PLoS One, 6:e28319, 2011.

　　17. Berquin, I.M., Edwards, I.J., O’Flaherty, J.T.and Chen*, Y.Q. Omega 3 PUFAs: Interventional trials for the preventionand treatment of breast and prostate cancer. In Dietary Omega-3 PolyunsaturatedFatty Acids and Cancer (G. Calviello ed.) pp149-166, 2010, Springer, New York,NY.

　　18. Edwards, I.J., Berquin, I.M., Chen, Y.Q.and O’Flaherty, J.T. Omega-3 PUFAs, breast and prostate cancer: Experimentalstudies. In Dietary Omega-3 Polyunsaturated Fatty Acids and Cancer (G.Calviello ed.) pp167-188, 2010, Springer, New York, NY.

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