承担科研项目：

 

　　1、国家自然科学基金（NO 21006010）: 新型智能双水相体系的构建、相行为与萃取分离性能研究;

 

　　2、教育部博士点新教师基金: 染料亲和-热敏新型双水相体系的构建、相行为与萃取分离性能研究;

 

　　3、传化集团：化学修饰精炼酶与助剂的协同增效机理研究;

 

　　4、中央高校基金：乳腺癌靶向治疗的智能纳米载药胶束的设计、制备和评价。

 

　　近几年发表论著：

 

　　1. B. Wang, P.Zhang, G.R. Williams, C.J. Branford-White, J. Quan, H.L. Nie*, L.M. Zhu. A simple route to form magnetic chitosan nanoparticles from coaxial-electrospun composite nanofibers. Journal of Materials Science, DOI 10.1007/s10853-013-7208-x, 2013.

 

　　2. S.F. Lou , H. Zhang, G.R. Williams, C.J. Branford-White, H.L. Nie, J. Quan, L.M. Zhu*.  Fabrication and aggregation of thermoresponsive glucose-functionalized doub le hydrophilic copolymers, Colloid Surface B-Biointerfaces, 105(5), 180-186, 2013.

 

　　3. H. Zhang, S.F. Lou, G.R Williams, C.J. Branford-White, H.L. Nie, J. Quan, L.M. Zhu*.  A systematic study of captopril-loaded polyester fiber mats prepared by electr ospinning. International Journal of Pharmaceutics, 439 (1-2), 100-108, 2012.

 

　　4. Y.Q. L, H.L. Nie, C.J. Branford-White, G.R. Williams, LM. Zhu, metal chelate affinity precipitation: Purification of BSA using poly(N-vinylcaprolactam-co-methacrylic acid) copolymers, Colloid Surfaces B-Biointerfaces, 94(1), 821-827, 2012.

 

　　5. L. Tian, C.J. Branford-White, W. Wang, H.L. Nie?, L.M. Zhu，Laccase-mediated system pretreatment to enhance the effect of hydrogen peroxide bleaching of cotton fabric，International Journal of Biological Macromolecules，50(3), 782–787, 2012.

 

　　6. M.M. Song, C.J. Brandford-white, H.L. Nie*, L.M. Zhu. Optimization of adsorption conditions of BSA on thermosensitive magnetic composite particles using response surface methodology. Colloids and Surfaces B: Biointerfaces, 84, 477-483, 2011.

 

　　7. L.Q. Tian, H.L. Nie, N.P. Chatterton, C.J. Branford-White, Y.P. Qiu, L.M. Zhu, Helium/oxygen atmospheric pressure plasma jet treatment for hydrophilicity improvement of grey cotton knitted fabric, Applied Surface Science, 257, 7113-7118, 2011.

 

　　8. M.M. Song, H.L. Nie, Y.T. Zhou, L.M. Zhu*, Jin-Yue Bao. Affinity adsorption of bromelain on Reactive Red 120 immobilized Magnetic composite particles. Separation Science and Technology, 46, 473-482, 2011.

 

　　9. Y. Xue, C.Y. Wu, C.J. Branford White, X. Ning, H.L. Nie*, L.M. Zhu*. Chemical modification of stem bromelain with anhydride groups to enhance its stability and catalytic activity. Journal of Molecular Catalysis B: Enzymatic, 63,188-193, 2010.

 

　　10. Z.Y. He, C.J. Branford White, Y.T. Zhou, H.L. Nie*, L.M. Zhu*. Papain adsorption on chitosan-coated nylon-based immobilized metal ion (Cu2+, Ni2+, Zn2+, Co2+) affinity membranes. Separation Science and Technology, 45, 1-10, 2010.

 

　　11. H.T. Zhang, C.Y. Wu, Y.L. Zhang, C.J. Branford White, Y. Xue, H.L. Nie*, L.M. Zhu. Elaboration, characterization and study of a novel affinity membrane made from electrospun hybrid chitosan/nylon-6 nanofibers for papain purification. Journal of Materials Science, 45, 2296-2304, 2010.

 

　　12. H.T. Zhang, H.L. Nie, D.G. YU, C.Y. Wu, Y.L. Zhang, C.J. Branford White, L.M. Zhu*. Surface modification of electrospun polyacrylonitrile nanofiber towards developing an affinity membrane for bromelain adsorption. Desalination, 256,141-147, 2010.

 

　　13. Y. Xue, H.L. Nie, L.M. Zhu*, S.B. Li. Immobilization of modified papain with anhydride groups on activated cotton fabric. Applied Biochemistry and Biotechnology, 160,109-121, 2010.

 

　　14. Y.Q. Ling, H.L. Nie, S.N. Su, C.J. Branford White, L.M. Zhu.Optimization of affinity partitioning conditions of papain in aqueous two-phase system using response surface methodology. Separation and Purification Technology, 73, 343–348, 2010.

 

　　15.  S.B. Li., H.L. Nie, H.T.Zhang, Y. Xue, C.J. Branford White, L.M. Zhu. Inhibitory Kinetics of a Trifluoromethyl-Containing 1,2,3-Triazole Derivative on Mushroom Tyrosinase Activity. Acta Physico-Chimica Sinica, 26, 215-220, 2010.

 

　　16. Ying-Qing Hu, Hua-Li Nie, Christopher Branford-White, Zheng Zhao, Li-Min Zhu*, Isolation and characterization of hemicelluloses from cottonseed coat, Journal of Biobased Materials and Bioenergy, 2010, 4, 446-451.