承担项目：

　　2014-2017   国家自然科学基金面上项目  在分枝杆菌中从简单碳源自给自足合成雄甾烯酮的研究

　　2013-2015   国家自然科学基金青年项目  细胞壁在Mycolata 类微生物摄取转化甾醇过程中的作用

　　2013-2014   企业横向课题  柠檬酸菌株基因工程改造

　　2011-2013   中央高校基本科研业务费  甾醇侧链C17-C20键断裂的机理及其基因调控在甾体药物生产过程中的作用

　　2011-2012   863项目子课题  柠檬酸、葡萄糖酸的生物转化技术   柠檬酸高品质生产菌株的研发

　　2008-2010   自然基金项目  具有新颖催化特征的S. virginiae新菌株降解薯蓣皂素、雌酮等甾类内分泌干扰物的新机制研究

　　2008-2010   863项目   基于类固醇药物生产相关重要生物转化反应的工程微生物的研发

　　代表论文(* corresponding author)：

　　1. Kang Yao, Feng-Qing Wang*, Huai-Cheng Zhang, Dong-Zhi Wei. Identification and engineering of cholesterol oxidases involved in the initial step of sterols catabolism in Mycobacterium neoaurum. metabolic Engineering, 2013, 15:75-87.

　　2. Miao-Miao Chen, Feng-Qing Wang*, Liang-Cai Lin, Kang Yao, Dong-Zhi Wei. Characterization and application of fusidane antibiotic biosynethsis enzyme 3-ketosteroid-?1-dehydrogenase in steroid transformation. Applied Microbiology and Biotechnology, 2012, 96:133-142.

　　3. Hengwei Wang, Fengqing Wang, Xinyi Tao Hairong Cheng. Ammonia-containing DMSO: An improved solvent for the dissolution of formazan crystals in the 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl tetrazolium bromide (MTT) assay. Analytical Biochemistry, 2012, 421:324-326.

　　4. Liangcai Lin, Weiguo Fang, Xinggang Liao, Fengqing Wang, Dongzhi Wei, Raymond J. St. Leger. The MrCYP52 cytochrome P450 monoxygenase gene of metarhizium robertsii is important for utilizing insect epicuticular hydrocarbons. PloS One. 2011, 6(12) e28984.

　　5. Liangcai Lin, Fengqing Wang*, Dongzhi Wei. Chlorimuron ethyl as a new selecable marker for disrupting genes in the insect-pathogenic fungus metarhizium robertsii. Journal of Microbiological Methods, 2011, 87:241-243.

　　6. Feng-Qing Wang, Kang Yao, Dongzhi Wei. from soybean phytosterols to steroid hormones. In Hany A. EI-Shemy (ed.) Soybean and Health. Intech, 2011, P231-252.

　　7.Hengwei Wang, Hairong Cheng, Dongzhi Wei, Fengqing Wang*. Comparison of methods for measuring viable E. coli cells during cultivation: Great differences in the early and late exponential growth phases. Journal of Microbiological Methods, 2011, 84:140-143.

　　8. Wei Wei, Fengqing Wang*, Shu-yue Fan, Dong-zhi Wei. Inactivation and augmentation of the main 3-ketosteroid- 1-dehydrogenase in Mycobacterium neoaurum NwIB-01: biotransformation of soybean phytosterols to 4-androstene-3,17-dione or 1,4-androstadiene-3,17-dione. Applied and Environmental Microbiology, 2010, 76:4578-4582.

　　9. Wei Wei, Shuyue Fan, Fengqing Wang*, Dongzhi Wei. A new steroid-transforming strain of Mycobacterium neoaurum and cloning of 3-ketosteroid 9α-hydroxylase in NwIB-01. Applied Biochemistry and Biotechnology. 2010, 162:1446-1456.

　　10. Bo Li, Wei Wang, Feng-Qing Wang*，Dong-Zhi Wei. Cholesterol oxidase ChoL is a critical enzyme that catalyzes the conversion of diosgnin to 4-ene-3-keto steroids in Streptomyces virginiae IBL-14. Applied Microbiology and Biotechnology, 2010, 85:1831-1838.

　　11. HengWei Wang, Fengqing Wang, Dongzhi Wei. Impact of oxygen supply on rtPA expression in Escherichia coli BL21 (DE3): ammonia effects. Applied Microbiology and Biotechnology, 2009, 82:249-259.

　　12. Feng-Qing Wang, Cheng-Gang Zhang, Bo Li, Dong-Zhi Wei, Wang-Yu Tong. New microbiological transformations of steroids by Streptomyces virginiae IBL-14. Environmental Science & Technology. 2009, 43:5967-5974.

　　13. Wei Wang, Feng-Qing Wang, Dong-Zhi Wei. Characterization of P450 FcpC, the enzyme responsible for bioconversion of diosgnone to isonuatigenone in Streptomyces virginiae IBL-14. Applied and Environmental Microbiology. 2009, 75:4202-4205.

　　14. Feng-Qing Wang, Bo Li, Wei Wang, Cheng-Gang Zhang, Dong-Zhi Wei.  Biotransformation of diosgenin to nuatigenin-type steroid by a newly isolated strain, Streptomyces virginiae IBL-14. Applied Microbiology and Biotechnology. 2007, 77:771-777.

　　荣誉和奖励：

　　2013  上海市技术发明一等奖成员

　　2012  上海市科技进步一等奖成员

　　2010  上海市科技进步一等奖成员