近期发表论文情况

　　１. Kefeng Ni,a, 1Huimin Lu,a, 1 Cunxun Wang,a Kvar C.L. Black,b, c Dongzhi Wei,a Yuhong Ren,a, * Phillip B. Messersmithb, c, 2. A novel technique for in situ aggregation of Gluconobacter oxydans using bio-adhesive magnetic nanoparticles. Biotechnology and Bioengineering.  2012 (Accepted 11 June, in press).

　　２. Kefeng Ni; Xu Zhou; Li Zhao; Hualei Wang; Yuhong Ren*; Dongzhi Wei. Magnetic catechol-chitosan with bioinspired adhesive surface: Preparation and immobilization of ω-transaminase. PLoS one. 2012 (Accepted 21 June. in press).

　　３. Yuhong Ren*, Jose G. Rivera, Lihong He, Harsha Kulkarni, Dong-Keun Lee?, Phillip B. Messersmith*. Facile, high efficiency immobilization of lipase enzyme on magnetic iron oxide nanoparticles via a biomimetic coating. BMC Biotechnology.2011, 11:63

　　４. Shiyu Fu, Changlei Sun, Xingyi Tao and Yuhong Ren*. Anti-inflammatory effects of active constituents extracted from Traditional Chinese Medicine herbs against Propionibacterium acnes. Natural Product Research. 2011（ DOI:10.1080/14786419.2011.608675）.

　　５. Jiaqi Wang , Xinyi Tao , Yufei Zhang, Dongzhi Wei, Yuhong Ren*. Reversion of multidrug resistance by tumor targeted delivery of antisense oligodeoxynucleotides in hydroxypropyl- chitosan nanoparticles. Biomaterials. 2010, 31，4426–4433.

　　６. Yuhong Ren, Yong Wang, Yufei Zhang, Dongzhi Wei *.Overcoming multidrug resistance in a human carcinoma cells by an antisense oligodeoxynucleotide-doxorubicin conjugate in vitro and in vivo. Molecular Pharmaceutics.2008，5（4）：579-587.

　　７. Jianguo Zhang, XuedongWang, Erzheng Su, Guochen Fang, Yuhong Ren, DongzhiWei. A new fermentation strategy for S-adenosylmethionine production in recombinant Pichia pastoris. Biochemical Engineering Journal 41 (2008) 74–78

　　８. Dengchao Li, Shiwei Cheng, dongzhi Wei, Yuhong Ren, Derong Zhang. Production of enantiomerically pury (S)-β-phenylalanine and (R) -β-phenylalanine by penicillin G acyladse from Escherichia coli in aqueous medium. Biotechnol. Lett (2007) 29:1825-1830.

　　９. Zhangyan Tao,Yuhong Ren*, Dongzhi Wei,Wangyu Tong. Synthesis of 6-O-acyl-L-ascorbic acid-2-O-phosphates and study of their antioxidant effects in 95-D cell. Pharmacological Reports. 2005,57:77-83.

　　１０. Yuhong Ren, Xiaoyun Zhan, Dongzhi Wei, Jianwen Liu. Inhibition of P-glycoprotein and increasing of drug sensitivity of human carcinoma cell line by an antisense oligodeoxynucleotide-doxorubicin conjugate in vitro. Biotechnology & Applied Biochemistry.2004;40:1-7

　　１１. Yuhong Ren, Dongzhi Wei. Quantification intracellular levels of oligodeoxynucleotide- doxorubicin conjugate in human carcinoma cells in situ. Journal of Pharmaceutical and Biomedicine Analysis. 2004;36:387-391

　　１２. Yuhong Ren, Dongzhi Wei, Jianwen Liu, Wu Su. An antisense oligodeoxynucleotide- doxorubicin conjugate: Preparation and its reversal multidrug resistance of human carcinoma cell line in vitro. Nucleosides, Nucleotides & Nucleic Acids.2004;23(10),1595-1607

　　１３. Yuhong Ren, Xiaoyun Zhan, Dongzhi Wei, Jianwen Liu. In vitro reversal MDR of human carcinoma cell line by an antisense oligodeoxynucleotide-doxorubicin conjugate. Biomedicine Pharmacotherapy.2004；58,520-526

　　１４. Du Changbing, Liu Jianwen, Su Wu, Ren Yuhong, Wei Dongzhi. The protective effect of ascorbic acid derivative on PC12 cells: Involvement of its ROS scavenging ability. Life science. 2003, 74: 771-780

　　１５. Ren YH, Wei DZh, Liu JW, Zhan XY. Study of the stability of oligodeoxynucleotide- doxorubicin conjugate in vitro and its pharmacokinetic in vivo by RP-HPLC. J Liq Chromato & Relat Tech 2003; 26: 3103-13.

　　１６. 周剑平，任宇红*，张敏洁，孙晓锋，魏东芝，毕赤酵母不对称合成阿托伐他汀中间体，生物工程学报，2011,27（4），579-583

　　１７. 张德荣，任宇红*，黄磊，魏东芝生物法合成达泊西汀，生物加工过程，2010，8（2）：13-17

　　１８. 汪吉忠，任宇红*，欧伶，张鲁嘉，魏东芝，反相高效液相色谱法对大鼠体内菲达司他的药代分析，生物加工过程，2008，6（4）：74-77

　　１９. 任宇红*，黄磊，张德荣，魏东芝，非达司他中间体的酶法拆分，精细化工，2008，25（4）：329-332.

　　２０. 叶素梅，任宇红*，魏东芝，2-脱氧-L-核糖的合成方法改进，精细化工，2007，24（11）：1099-1101.

　　近期申请的专利：

　　1、魏东芝, 任宇红,詹晓云. 寡聚核苷酸与阿霉素共价偶联物及其制备方法. 中国专利，授权专利号：CN0315474.X。

　　2、任宇红，张宇飞，魏东芝，王佳琪，由叶酸受体介导的靶向性壳聚糖类载体及制备方法和应用，中国专利,公开号：CN101032623。

　　3、任宇红，黄磊，魏东芝，( 2s) -6- 氟-3,4-二氢-4- 氧代-2H-1-苯并吡喃-2- 羧酸的制备方法，中国专利,授权专利号：ZL 200710044016.2。

　　4、任宇红，黄磊，陶欣艺，魏东芝，哌啶基吡唑类化合物的制备与应用，中国专利，授权号：CN 200710044279.3

　　5、魏东芝,任宇红，吴娉娉，陶欣艺，一类新型PI3K酶抑制剂及其应用，中国专利,申请号：200810036220.4。

　　6、任宇红，周剑平，张敏洁、朱丽平，魏东芝，（S）-3-羟基-5-邻苯二甲酰亚氨基戊酸乙酯的制备方法，中国专利,申请号：200910200767.8。