2014年获得江苏省高校“青蓝工程”中青年学术带头人荣誉和资助。

　　主要研究方向：

　　1、食品功能成分（或天然活性产物）富集、分离纯化、分子修饰、生物活性及相关构效关系；

　　2、（天然活性产物）生物催化与生物转化；

　　3、农副产品精深加工。

　　主持和参与国家自然科学基金、教育部、江苏省及其他省部级基金多项。多次与企业合作开发新产品，具有丰富的从产品研发到市场转化经验。

　　共发SCI论文多篇；第一作者IF大于5.0的SCI论论2篇，最高影响因子为5.836（Green Chemistry, 2009, 11: 1743–1745），这是食品院建院以来第一篇IF突破5.0的研究论文；另1篇为Bioreource Technology（IF 5.039, 2013, 133: 82－86）。目前为止，发表的SCI论文被引用的次数达100余次。申请国家发明专利30余项，获得授权的国家发明专利10余项。

　　对天然活性化成分（如魔芋葡苷聚糖、百合多糖、穿心莲内酯及虫草素等）的分离纯化、酶法修饰及相关活性研究发表在SCI期刊上，并受到同行的好评。相关研究成果被国际化学类影响因子最高杂志（2次）Chemical Reviews（IF 35.957）及国际知名的生物大分子类杂志（1次）Biomacromolecules评述及引用（详见Fred van Rantwijk and Roger A. Sheldon. Chemical Reviews, 2007, 107: 2757- 2785；Kobayashi S and Makino A. Chemical Reviews, 2009, 109: 5288–5353; EI Seoud O A, Koschella A, Fidale L C, et al. Biomacromolecules, 2007, 8: 2629-2646）。

　　发表论文

　　*为通讯作者

　　2015

　　1 Fen Wang, Xiao-Yu Guo, Dan-Ni Zhang, Yue Wu, Tao Wu, Zhi-Gang Chen*. Ultrasound- assisted extraction and purification of taurine from the red algae Porphyra yezoensis. Ultrasonics Sonochemistry, 24 (2015) 36–42

　　2014

　　1 Zhi-Gang Chen*, Dan-Ni Zhang, Qu Zhu, Qiu-Huizi Yang, Yong-Bin Han. Purification, preliminary characterization and in vitro immunomodulatory activity of tiger lily polysaccharide. Carbohydrate Polymers 106 (2014) 217–222

　　2 Dan-Ni Zhang, Xiao-Yu Guo, Qiu-Huizi Yang, Zhi-Gang Chen*, Li-Jia Tao.

　　An efficient enzymatic modification of cordycepin in ionic liquids under ultrasonic irradiation. Ultrasonics Sonochemistry 21 (2014) 1682–1687

　　3 Dan-Ni Zhang, Xiao-Yu Guo, Zhi-Gang Chen*. A novel and efficient method for the isolation and purification ofpolysaccharides from lily bulbs by Saccharomyces cerevisiae fermentation. Process Biochemistry 49 (2014) 2299–2304

　　2013

　　1 Zhi-Gang Chen*, Dan-Ni Zhang, Lin Cao, Yong-Bin Han. Highly efficient and regioselective acylation of pharmacologically interesting cordycepin catalyzed by lipase in the eco-friendly solvent 2-methyltetrahydrofuran.

　　Bioresource Technology 133 (2013) 82–86

　　2 Zhi-Gang Chen*, Dan-Ni Zhang, Yong-Bin Han. Lipase-catalyzed acylation of lily polysaccharide in ionic liquid-containing systems. Process Biochemistry 48 (2013) 620–624

　　3 Fen Wang, Zhi-Gang Chen*, Hui-Jie Zhu. An efficient enzymatic modification of lily polysaccharide in ionic liquid under ultrasonic irradiation. Biochemical Engineering Journal 79 (2013) 25– 28

　　4 Zhi-Gang Chen, Monika A Zie?tek, Henry J. Russell, Shirley Tait, Sam Hay, Alex R. Jones, and Nigel S. Scrutton. Dynamic, Electrostatic Model for the Generation and Control of High-Energy Radical Intermediates by a Coenzyme B12-Dependent Enzyme. ChemBioChem 2013, 14, 1529 – 1533

　　2011-2009

　　1 Chen Z.G. *, Zhu Q., Zong M.H., Gu Z.X., Han Y.B. Enzymatic synthesis and antibacterial activity of andrographolide derivatives. Process Biochemistry, 2011, 46, 1649-1653.

　　2 Chen Z.G.*, Tan R.X., Huang Mi. Efficient regioselective acylation of andrographolide catalyzed by immobilized Burkholderia cepacia lipase. Process Biochemistry, 2010, 45, 415-418.

　　3 Zhi Gang Chen*, Ren Xiang Tan and Lin Cao. Efficient and highly regioselective acylation of andrographolide catalyzed by lipase in acetone. Green Chemistry, 2009, 11, 1743–1745

　　4 Chen, Zhigang*, Zong, Minhua, Gu, Zhenxin. Toxicity, Biodegradability and Design and Synthesis of Green Ionic Liquids, Chinese Journal of Organic Chemistry，2009, 29(5):672-680

　　5 Zhi Gang Chen*, Ren Xiang Tan, Ming Huang. Efficient regioselective acylation of andrographolide catalyzed by Immobilized Burkholderia cepacia lipase. Process Biochemistry , 2010, 45, 415-418

　　6  Hongfei Yin, Zhigang Chen, Zhenxin Gu, Yongbin Han. Optimization of natural      fermentative medium for selenium-enriched yeast by D-optimal mixture design.

　　LWT - Food Science and Technology , 2009, 42(1): 327-331

　　2008-2006

　　1 Chen Z G, Zong M H, Gu Z X, Han Y B.  Effect of ultrasound on enzymatic

　　acylation of konjac glucomannan. Bioprocess Biosystem Engineering, 2008, 31:351–356

　　2 Xiaoxue Lu, Zhigang Chen, Zhenxin Gu, Yongbin Han. Isolation of γ-aminobutyric acid-producing bacteria and optimization of fermentative medium. Biochemical Engineering Journal , 2008, 41: 48-52

　　3 Chen Z G*, Han Y B, Gu Z X. Effect of ultrasonic irradiation on enzymatic

　　modification of  konjac   glucomannan. Polymer Preprints, 2007, 48(1), 394-395（Division of Polymer Chemistry，232th ACS National Meeting）

　　4 Chen, Zhi-Gang*, Zong, Min-Hua. Effects of molecular mass and acyl donors on enzymatic acylation of konjac glucomannan. Chinese Journal of Catalysis , 2007, 28(4): 339-344

　　5 Chen, Zhi-Gang*, Zong, Min-Hua, Gu, Zhen-Xin.  Enzymatic synthesis of sugar esters in ionic liquids. Chinese Journal of Organic Chemistry, 2007, 27(11): 1448-1452

　　6 陈志刚，宗敏华，娄文勇. 非水介质中酶促糖酯合成研究进展. 分子催化, 2007, 21(1): 90-95

　　7  Chen Z G, Zong M H, Li G J. Lipase-catalyzed regioselective acylation of konjac glucomannan in ionic liquids. Polymer Preprints, 2006, 47(1): 169-170

　　（Division of Polymer Chemistry，231th ACS National Meeting；Atlanta GA）

　　8 Chen Z G, Zong M H, Li G J. Lipase-catalyzed acylation of konjac glucomannan in organic media. Process Biochemistry (IF 2.414), 2006, 41(7): 1514-1520

　　9 Chen Z G, Zong M H, Li G J. Lipase-catalyzed acylation of konjac glucomannan in ionic liquids. Journal of Chemical Technology & Biotechnology , 2006, 81(7): 1225-1231

　　10  Chen Z G, Zong M H, Li G J. Lipase-Catalyzed Modification of Konjac Glucomannan. Journal of applied polymer science，2006, 102(2): 1335-1440

　　11Chen Z G, Zong M H, Li G J, Ding R. Lipase-catalyzed acylation of konjac glucomannan in a solvent-free system. Polymer Preprints, 2005, 46(2): 679-680

　　授权专利

　　1、生物催化制备穿心莲内酯酯化衍生物的方法 ZL  200910033534.3

　　2、发酵法提取百合多糖的生产工艺及其产品 ZL  201010017677.8

　　3、一种即食性湿态调味紫菜产品及其生产工艺 ZL 200910024953.0

　　4、一种生物催化制备虫草素酯化衍生物的方法 ZL 201110163423.1

　　5、一种生物催化制备百合多糖酯化衍生物的方法 ZL 201210172982.3

　　6 一种同时有效去除紫菜提取液中紫菜蛋白和紫菜多糖的方法 ZL201310404659.9